SkinCare Physicians Doctors

A New Era in Psoriasis Care: Icotyde Offers Powerful Results Without Injections

Published on Jun 23rd, 2026 by Jeffrey Sobell, MD

Dr Sobell holding the-new ICOTYDE pill in one hand and the box in the other.There is exciting news for people living with moderate-to-severe plaque psoriasis: The recent approval of the daily pill Icotyde.

What makes Icotyde different?

The FDA approved Icotyde (icotrokinra) provides a new treatment option that combines convenience, effectiveness, and an excellent safety profile for adults and adolescents aged 12 years and older.

Convenience: One of the most notable strengths of Icotyde is that it is a once-daily oral medication. For many patients, taking a pill may feel more approachable and convenient than receiving injections. This may be especially important for adolescents and others who are uncomfortable with needles, believes Dr. Sobell, a psoriasis expert.

Excellent safety profile: Icotyde has also demonstrated an impressive safety profile in clinical trials. The rate of side effects was comparable to placebo, providing reassurance for patients and healthcare providers considering long-term treatment.

Efficacy: Just as important, Icotyde works well. Clinical trial results showed that approximately seven out of ten patients achieved clear or almost clear skin after 16 weeks of treatment. By week 24, one out of every two patients achieved completely clear skin, highlighting the medication’s ability to deliver meaningful improvement for many individuals living with psoriasis.

How does Icotyde work

Psoriasis occurs when the immune system mistakenly speeds up the growth of skin cells, leading to thick, scaly, and inflamed patches of skin. Icotyde works by blocking a specific immune system signal called IL-23, which plays a key role in causing psoriasis.

Physicians at the Psoriasis Treatment Center at SkinCare Physicians participated in the clinical research that helped evaluate Icotyde, giving our team firsthand experience with this important new therapy. Our providers are skilled in assessing all severities of psoriasis and can discuss in detail whether Icotyde may be an appropriate treatment option for you.

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SkinCare Physicians®

1244 Boylston Street (Route 9)
Chestnut Hill, Massachusetts 02467

Learn more about your rights and protections related to the No Surprises Act (HR133).

The dermatologists and other medical professionals at SkinCare Physicians specialize in a wide range of dermatology treatments and services, including laser hair removal, laser skin treatment, hair transplant, eyelid surgery, body contouring, psoriasis, skin cancer, BOTOX® Cosmetic, fillers, and Thermage®. From their offices in Chestnut Hill, they serve Boston, Brookline, Cambridge, Newton and Wellesley.

Keep in mind that each patient is unique and your results may vary.



SkinCare Physicians®
1244 Boylston Street (Route 9)
Chestnut Hill, Massachusetts 02467

Phone: (617) 731-1600 Fax: (617) 731-1601

Learn more about your rights and protections related to the No Surprises Act (HR133).

Keep in mind that each patient is unique and your results may vary.

The dermatologists and other medical professionals at SkinCare Physicians specialize in a wide range of dermatology treatments and services, including laser hair removal, laser skin treatment, hair transplant, eyelid surgery, body contouring, psoriasis, skin cancer, BOTOX® Cosmetic, fillers, and Thermage®. From their offices in Chestnut Hill, they serve Boston, Brookline, Cambridge, Newton and Wellesley.