SkinCare Physicians Doctors

Novel therapy takes clearance of psoriasis to new heights

Published on Jun 13th, 2019 by Jeffrey Sobell, MD

Psoriasis expert Dr. Jeff Sobell entering data on his iPadOver the last 2 decades, SkinCare Physicians’ Dr. Jeff Sobell has experienced a progression in innovative therapies for psoriasis. Now, with the recent approval of Skyrizi (rizankizumab-rkaa), a biologic indicated for the treatment of moderate-to-severe plaque psoriasis, this progress continues.

Skyrizi belongs to an exciting new class of medications called IL-23 inhibitors. These medications, given by subcutaneous injection, have gained in popularity as they offer patients the chance for high efficacy with favorable tolerability.
In clinical trials with Skyrizi, the average patient’s psoriasis improved by over 50% after 1 dose, and over 90% after 2 doses. At one year after 4 doses, with one injection every 3 months, the average patient’s psoriasis was 95% clear. Not only did Skyrizi address the redness, scale and thick appearance of psoriasis, but it also relieved the symptoms of itching, burning and pain frequently associated with the skin disease.

Before & After Photos Plaque Psoriasis Treated with Skyrizi

Plaque psoriasis on back of patient before Skyrizi treatment Plaque psoriasis on back of patient at 4 weeks of Skyrizi treatment Plaque psoriasis on back of patient at 16 weeks of Skyrizi treatment
Before Skyrizi treatment At 4 weeks of treatment At 16 weeks of treatment

Overall the medication was well tolerated by patients in the investigational studies.  Common side effects included upper respiratory tract infections, headache and fatigue.  As with most biologic therapies, testing for past exposure to tuberculosis is required before starting therapy.

If you suffer from psoriasis, it’s time to contact SkinCare Physicians’ Psoriasis Treatment Center. Skyrizi is an example of the innovative and effective treatments available at our practice. Our dermatologists are proud to provide our psoriasis patients with the very best care possible.

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SkinCare Physicians®

1244 Boylston Street (Route 9)
Chestnut Hill, Massachusetts 02467

Learn more about your rights and protections related to the No Surprises Act (HR133).

The dermatologists and other medical professionals at SkinCare Physicians specialize in a wide range of dermatology treatments and services, including laser hair removal, laser skin treatment, hair transplant, eyelid surgery, body contouring, psoriasis, skin cancer, BOTOX® Cosmetic, fillers, and Thermage®. From their offices in Chestnut Hill, they serve Boston, Brookline, Cambridge, Newton and Wellesley.

Keep in mind that each patient is unique and your results may vary.



SkinCare Physicians®
1244 Boylston Street (Route 9)
Chestnut Hill, Massachusetts 02467

Phone: (617) 731-1600 Fax: (617) 731-1601

Learn more about your rights and protections related to the No Surprises Act (HR133).

Keep in mind that each patient is unique and your results may vary.

The dermatologists and other medical professionals at SkinCare Physicians specialize in a wide range of dermatology treatments and services, including laser hair removal, laser skin treatment, hair transplant, eyelid surgery, body contouring, psoriasis, skin cancer, BOTOX® Cosmetic, fillers, and Thermage®. From their offices in Chestnut Hill, they serve Boston, Brookline, Cambridge, Newton and Wellesley.